Ophthalmology disorders are associated with the eyes and visual system. If left untreated, serious long-term co-morbidities such as diabetes, and particularly blindness, can arise. Although there are a number of treatments approved in ophthalmology, there are currently no curative therapies for any of these indications. In particular, there are strong unmet needs within age-related macular degeneration and glaucoma, which can lead to blindness if not adequately treated.
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Although there is a high degree of failure and uncertainty within the R&D of pharmaceuticals, there is a great deal of interest in ophthalmology development. Overall, there are over 700 products in active development in the ophthalmology therapy area, making it one of the largest therapy area pipelines.
Although two thirds of products in development for ophthalmology disorders are at the Discovery or Preclinical stage of development, the number of drugs in the pipeline is very high, creating strong potential for a blockbuster drug to enter the market.
The report provides comprehensive information on the pipeline development landscape for glaucoma, age-related macular degeneration, diabetic retinopathy, diabetic macular edema and keratoconjunctivitis sicca (dry eye), from Discovery through to the Pre-Registration stage. This includes an analysis of products by stage of development, molecular target, mechanism of action (MoA), route of administration (RoA) and molecule type. A list of all products in development is provided, including dormant and discontinued projects. Finally, the report provides an overview of key players involved in the development of products in this area, and outlines recent updates and press releases in the field.
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- Which companies are the most active within the pipeline for ophthalmology?
– Which pharmaceutical approaches are the most prominent at each stage of the pipeline and within each indication?
– To what extent do universities and institutions play a role within this pipeline, compared to pharmaceutical companies?
– What are the most important R&D milestones and data publications to have occurred in ophthalmology?
Reasons to buy
- Understand the overall pipeline, with an at-a-glance overview of all products in therapeutic development for each indication.
– Assess the products in development in granular detail, with an up-to-date overview of each individual pipeline program in each indication, and a comprehensive picture of recent updates and milestones for each.
– Analyze the companies, institutions and universities currently operating in the pipeline, and the products being fielded by each of these.
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Table of Content:
1 Table of Contents 4
1.1 List of Tables 5
1.2 List of Figures 13
2 Introduction 15
2.1 Ophthalmology Therapeutics Report Coverage 15
3 Therapeutics Development by Stage 18
3.1 Age Related Macular Degeneration 18
3.2 Diabetic Retinopathy 20
3.3 Diabetic Macular Edema 22
3.4 Keratoconjunctivitis sicca (Dry Eye) 24
3.5 Glaucoma 26
4 Therapeutics under Development by Companies 28
4.1 Age Related Macular Degeneration 28
4.2 Diabetic Retinopathy 39
4.3 Diabetic Macular Edema 42
4.4 Keratoconjunctivitis sicca (Dry Eye) 46
4.5 Glaucoma 50
5 Therapeutics under Investigation by Universities/Institutes 56
5.1 Age Related Macular Degeneration 56
5.2 Diabetic Retinopathy 57
5.3 Diabetic Macular Edema 57
5.4 Keratoconjunctivitis sicca (Dry Eye) 58
5.5 Glaucoma 58
6 Pipeline Products Glance 60
6.1 Age Related Macular Degeneration 60
6.2 Diabetic Retinopathy 64
6.3 Diabetic Macular Edema 66
6.4 Keratoconjunctivitis sicca (Dry Eye) 69
6.5 Glaucoma 72
7 Products under Development by Companies 76
7.1 Age Related Macular Degeneration 76
7.2 Diabetic Retinopathy 90
7.3 Diabetic Macular Edema 94
7.4 Keratoconjunctivitis sicca (Dry Eye) 98
7.5 Glaucoma 102
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