Chromatography methods are used to organic and inorganic compounds such as separate proteins, nucleic acids, or small molecules in complex mixtures and others. Liquid chromatography (LC) separates molecules in a liquid mobile phase by means of a solid stationary phase. It is basically a technique which separates a sample into its individual parts. This separation takes place based on the interactions of the sample with the mobile and stationary phases. Liquid chromatography procedure can be directed in various combination of possible mobile phases and stationary phases. The combinations are categorized with more than one name and the names focus on many different aspects of liquid chromatography methods. Liquid chromatography generally uses small particles packed and operating at comparatively high pressure, and is denoted as high performance liquid chromatography (HPLC). Modern Liquid Chromatography-Mass Spectrometry (LC-MS) methods use HPLC instrumentation, basically for sample introduction. Liquid chromatography can be used for analytical or preparative applications. Irrespective of the interactions that are being brought, liquid column chromatography is taken up in six steps: Column equilibration, Sample loading, Washing, Elution, Final column washing and Column regeneration.
Liquid Chromatography Systems Market: Drivers and Restraints
Liquid chromatography is a less expensive procedure than HPLC and Gas Chromatography. This could be considered as a most significant driving factor responsible for the growth of liquid chromatography systems market. Moreover some instruments for liquid chromatography are readily available in laboratories which is further providing boost to the growth of growing liquid chromatography systems market. However, limited sensitive and specific of detectors in applications involving complex samples could be the major restraints for liquid chromatography systems market.
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Liquid Chromatography Systems Market: Segmentation
Liquid chromatography systems market is segmented based on product type, applications, end user and geography.
Based on product type, liquid chromatography systems market is segmented as follows:
- Normal-phase liquid chromatography (NPLC)
- Reversed-phase liquid chromatography
- Ion Exchange Chromatography (IELC)
- Size exclusion liquid chromatography (SELC)
Based on applications, liquid chromatography systems market is segmented as follows:
- Food Product Analysis
- Oils and fats Analysis
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Based on end user, liquid chromatography systems market is segmented as follows:
- Research laboratories
- Clinical Research Laboratories
- Food Safety Laboratories
- Diagnostic centers
- Educational Institutes
- Contract Research Organizations
Liquid Chromatography Systems Market: Overview
In partition chromatography method, the stationary phase and the mobile phase both are liquid. The stationary phase liquid would be an incompatible liquid with the mobile phase. Liquid-solid chromatography is related to partition chromatography. The only difference is that the stationary phase has been substituted with a bonded rigid silica or silica based component. Ion-exchange chromatography technique is used to separate and determine ions on columns that have a low ion exchange capacity. Size exclusion chromatography separates molecules by their size. Further technological advancements have improved the convenience and ease of use of liquid chromatography devices.
Liquid Chromatography Systems Market: Region-wise Outlook
The global liquid chromatography systems marketis classified into seven regions namely, North America, Latin America, Western Europe, Eastern Europe, Asia-Pacific excluding Japan (APEJ), Japan, Middle East and Africa (MEA). North America is expected to dominate the liquid chromatography systems market in terms of both revenue and demand generation owing to greater awareness on technological advancement followed by Western Europe. However, markets in Latin America and Asia-Pacific could prove lucrative in terms of market opportunities considering factors like organized healthcare structure in terms of disease diagnosis, increasing initiatives for food safety and food detection and increasing healthcare spending.
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Liquid Chromatography Systems Market: Key Players
Some of the major companies operating in manufacturing of liquid chromatography systems include Thermo Fisher Scientific Inc., Agilent Technologies, PerkinElmer, Inc., Shimadzu Corporation, Waters Corporation, Phenomenex, Inc. among others.